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Pharmacokinetics and Pharmacodynamics

Toxicology Case Study: Acetaminophen Poisoning

Toxicology Case Study: Acetaminophen Poisoning History: A 20-year-old female presents to the Emergency Department after ingesting over 50 tablets of Tylenol Extra Strength® eight hours prior to arrival in a suicide attempt. She denies coingestants and complains of nausea. PMH: None. Physical Examination: T: 99 °F HR: 90 bpm RR: 12 breaths per minute BP: […]

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Date: August 12th, 2024

Gyromitra esculenta Toxicity Clinical Presentation

Gyromitra esculenta Toxicity: Clinical Presentation, Mortality, and Mechanisms This paper examines the toxicity associated with Gyromitra esculenta mushroom ingestion, focusing on clinical manifestations, mortality rates, therapeutic approaches, and the underlying mechanisms of toxicity. Signs and Symptoms of Gyromitra esculenta Toxicity Gyromitra esculenta, commonly known as the false morel, contains the toxin gyromitrin, which is metabolized […]

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Date: July 4th, 2024

Case Study: Acetaminophen Overdose in a Young Adult

Case Study: Acetaminophen Overdose in a Young Adult History: A 22-year-old female presents to the emergency department with complaints of nausea, vomiting, and abdominal pain. The patient reports ingesting approximately 50 tablets of extra-strength acetaminophen (500 mg each) 36 hours ago in a suicide attempt. She initially felt fine but developed symptoms over the past […]

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Date: July 4th, 2024

Clonidine Overdose: Clinical Presentation and Management

Clonidine Overdose: Clinical Presentation and Management Clonidine overdose presents a significant clinical challenge, particularly in elderly patients with comorbidities. This paper examines the signs and symptoms, decontamination methods, antidote options, and management strategies for clonidine toxicity, with special consideration for transdermal preparations. Signs and Symptoms of Clonidine Overdose Clonidine overdose manifests through a constellation of […]

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Date: July 4th, 2024

Complications and Management of Sustained-Release Diltiazem Overdose

Complications and Management of Sustained-Release Diltiazem Overdose Diltiazem overdose presents significant challenges in emergency medicine due to its potential for severe cardiovascular complications. This paper examines the complications associated with sustained-release diltiazem overdose and discusses appropriate management strategies, including gastrointestinal decontamination and supportive care. Complications of Sustained-Release Diltiazem Overdose Sustained-release diltiazem overdose can lead to […]

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Date: July 4th, 2024

A 28-year-old female is brought to the emergency department by paramedics

Opioid Overdose: Emergency Management and Pharmacological Interventions Case Study: A 28-year-old female is brought to the emergency department by paramedics after being found unresponsive in her apartment. The patient’s roommate reports she has a history of heroin use. Vital Signs: Temperature: 35.8°C (96.4°F) Heart Rate: 42 bpm Respiratory Rate: 6 breaths per minute Blood Pressure: […]

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Date: July 1st, 2024

Assessing and Treating Clients with Alzheimer Disease

Assessing and Treating Clients with Alzheimer Disease Introduction Alzheimer’s disease is a progressive neurological disorder that profoundly impacts millions of lives worldwide. It is a neurodegenerative condition characterized by cognitive and behavioral impairment, which considerably affects social and occupational functioning. It is an irreversible, gradually worsening disease that affects the brain’s memory and thinking abilities. […]

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Date: June 26th, 2024

Discussion: Pharmacokinetics and Pharmacodynamics

Discussion: Pharmacokinetics and Pharmacodynamics Patient Case: The case involves a 65-year-old Caucasian male diagnosed with Neurocognitive disorder. The patient has a history of hypertension, benign prostate hyperplasia, and a family history of Alzheimer’s. The wife reported an increase in anxiety, agitation, and confusion. Medications include Seroquel, Norvasc, Flomax, Namenda, and Remeron. Despite scheduled medications, the […]

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Date: January 10th, 2024

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